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Test Name

Detection of PML-RARA fusion gene; t(15;17) (q22;q21)

Gene Name

  • PML-RARA fusion gene

Division

Haematopathology- Molecular Haematology

Method

RT PCR (Real-time polymerase chain reaction) (end point)

External Proficiency Testing

CAP

Turn Around Time

2-3 working days

Disease/Condition

AML (Acute myeloid leukemia)

Clinical Significance

PML-RARA fusion gene is detected in greater than 99% of cases of acute promyelocytric leukemia (APL) which is associated with a favorable prognosis.

Specimen Type

Peripheral Blood, Bone Marrow Aspirate

Minimum Specimen Requirements

2 mL

Storage/Transportation

Room Temperature (on ice if shipping takes more than 48 hrs).

Special Requirements

Sample to be collected in EDTA  or Sodium citrate(preservative) Please call Laboratory prior to shipping your samples.

Shipping and Contact Information

The Hospital for Sick Children
Rapid Response Laboratory
170 Elizabeth Street, Room 3642
Toronto, ON
M5G 2G3
Canada
Phone: 416-813-7200
Phone: 1-855-381-3212

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